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Focus of research work in my laboratory is on understanding the
structure, function and modification of biointerface. Biointerface
is the plane where biology meets with non-biological systems, such
as in implantable devices.
Studies of biointerface has become critical in many disciplines
including biotechnology and medical that involve the use of live
cells, in vitro or
when prostheses are implanted in the body. Cells and tissues modify
their behavior based on their environment. For example, cells are
capable of feeling the 'sleep number' of the matrix, called extra
cellular matrix (ECM) through their mechano-sensors and grow only on
the suitable surface.
Work done previously in my laboratory has shown that surface
features (nanotopology developed with nanofibers) along with
chemical surface modification prolong life of mammalian cells and
stem cells. This phenomenon is not unique to animal cells; plant
cells also show somewhat similar response and modify growth pattern
depending upon the environment. If you are excited about
laboratory work with cells, plants or biomolecules, come and spend
some time in the biotechnology lab.
Model Research Systems
We work with Plant, animal and
stem cells. Techniques used in our research work are mammalian cell
and stem cell culture and plant tissue culture.
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